Married since 15 April 2006. Started living together in 2002.
Sandino Moreno lived with motion picture electrician David Elwell from 2002 to 2008, whom she met working on Maria Full of Grace. She married him on 15 April 2006 in a small ceremony held in Cartagena de Indias.
In 2009 she gave birth to her first child, a boy, in New York City.