Eventually Liberace came to showcase Cardell's piano abilities alongside him on stage, introducing him as his protégé.[3] As Cardell became more integral to Liberace's act, they would wear identical outfits while performing duets. Cardell lived at Liberace's home for six years, and although Vince was married and had children, Scott Thorson thought that Cardell and Liberace were almost certainly lovers. Liberace produced Cardell's first albums, and he toured with Cardell until their personal relationship soured and their contractual obligations came to an end in 1981.
Cardell's playing and flashy costumes were much like his mentor. He was reviewed as having a pleasant musical style, but with a tendency to play in an "overblown" manner.