| Cavalcade of America | 1952 | Moran | TV Show |
| Mr. & Mrs. North | 1952 | Rowdy | TV Show |
| The Ford Television Theatre | 1952 | Philly the Weeper | TV Show |
| Danger Zone | 1951 | Prof. Frederick Simpson Schicker | Movie |
| Pier 23 | 1951 | Prof. Shicker | Short Film |
| Roaring City | 1951 | 'Professor' Frederick Simpson Schicker | Short Film |
| Arson, Inc. | 1949 | Pete Purdy | Movie |
| The Price of Freedom | 1949 | Man in restaurant (uncredited) | Short Film |
| It Happened on Fifth Avenue | 1947 | Cecil Felton | Movie |
| Swing Parade of 1946 | 1946 | Moose (as Edward S. Brophy) | Movie |
| The Falcon's Adventure | 1946 | Goldie Locke (as Edward S. Brophy) | Movie |
| Renegade Girl | 1946 | Bob Crandall | Movie |
| Sweetheart of Sigma Chi | 1946 | Arty | Movie |
| Girl on the Spot | 1946 | Fingers Foley (as Edward S. Brophy) | Movie |
| The Falcon in San Francisco | 1945 | Goldie Locke (as Edward S. Brophy) | Movie |
| Wonder Man | 1945 | Torso | Movie |
| I'll Remember April | 1945 | Shadow (as Edward S. Brophy) | Movie |
| See My Lawyer | 1945 | Otis Fillmore (as Edward S. Brophy) | Movie |
| Penthouse Rhythm | 1945 | Bailey | Movie |
| Cover Girl | 1944 | Joe (uncredited) | Movie |
| It Happened Tomorrow | 1944 | Jake Shomberg | Movie |
| The Thin Man Goes Home | 1944 | Brogan | Movie |
| A Night of Adventure | 1944 | Steve | Movie |
| Air Force | 1943 | Marine Sgt. J.J. Callahan (as Edward S. Brophy) | Movie |
| Destroyer | 1943 | Casey (as Ed Brophy) | Movie |
| A Scream in the Dark | 1943 | Eddie Tough (as Edward S. Brophy) | Movie |
| Lady Bodyguard | 1943 | Harry Gargan | Movie |
| Larceny, Inc. | 1942 | Weepy Davis | Movie |
| Broadway | 1942 | Porky (as Edward S. Brophy) | Movie |
| Madame Spy | 1942 | Mike Reese (as Edward S. Brophy) | Movie |
| All Through the Night | 1941 | Joe Denning | Movie |
| Dumbo | 1941 | Timothy Q. Mouse (voice, uncredited) | Movie |
| Sleepers West | 1941 | George Trautwein | Movie |
| The Bride Came C.O.D. | 1941 | Hinkle | Movie |
| The Gay Falcon | 1941 | Detective Bates | Movie |
| A Dangerous Game | 1941 | Bugsy (misspelled Bugs in on-screen credits) | Movie |
| Buy Me That Town | 1941 | Ziggy | Movie |
| Nine Lives Are Not Enough | 1941 | Officer Slattery | Movie |
| Steel Against the Sky | 1941 | Pete Evans | Movie |
| Thieves Fall Out | 1941 | Rork | Movie |
| Dance, Girl, Dance | 1940 | Dwarfie | Movie |
| The Great Profile | 1940 | Sylvester | Movie |
| The Invisible Woman | 1940 | Bill | Movie |
| Calling Philo Vance | 1940 | Ryan | Movie |
| Golden Gloves | 1940 | Potsy Brill | Movie |
| Alias the Deacon | 1940 | Stuffy | Movie |
| Sandy Gets Her Man | 1940 | Fireman Junior | Movie |
| Golden Boy | 1939 | Roxy Lewis (as Edward S. Brophy) | Movie |
| Mr. Smith Goes to Washington | 1939 | Newspaper Employee (uncredited) | Movie |
| You Can't Cheat an Honest Man | 1939 | Corbett | Movie |
| Kid Nightingale | 1939 | Mike Jordon (as Ed Brophy) | Movie |
| Society Lawyer | 1939 | Max (as Edward S. Brophy) | Movie |
| The Amazing Mr. Williams | 1939 | Buck Moseby (as Edward S. Brophy) | Movie |
| The Big Guy | 1939 | Dippy | Movie |
| The Kid from Kokomo | 1939 | Eddie Black (as Ed Brophy) | Movie |
| For Love or Money | 1939 | Sleeper | Movie |
| Pardon Our Nerve | 1939 | Nosey Nelson | Movie |
| A Slight Case of Murder | 1938 | Lefty | Movie |
| Gold Diggers in Paris | 1938 | Mike Coogan (as Ed Brophy) | Movie |
| Come On, Leathernecks! | 1938 | Max 'Curly' Maxwell | Movie |
| Hold That Kiss | 1938 | Al (as Edward S. Brophy) | Movie |
| Gambling Ship | 1938 | Cuthbert Innocent (as Ed Brophy) | Movie |
| Passport Husband | 1938 | Spike (as Edward S. Brophy) | Movie |
| Romance on the Run | 1938 | Whitey Whitehouse | Movie |
| Vacation from Love | 1938 | Barney Keenan, Band Leader | Movie |
| The Last Gangster | 1937 | 'Fats' Garvey (as Edward S. Brophy) | Movie |
| The Soldier and the Lady | 1937 | Packer | Movie |
| Varsity Show | 1937 | Mike Barclay (as Ed Brophy) | Movie |
| The Hit Parade | 1937 | Mulrooney | Movie |
| Jim Hanvey, Detective | 1937 | Romo (as Edward S. Brophy) | Movie |
| The Girl Said No | 1937 | Pick | Movie |
| The Great Gambini | 1937 | 'Butch' | Movie |
| Blossoms on Broadway | 1937 | Mr. Prussic | Movie |
| Oh, Doctor | 1937 | Meg Smith | Movie |
| Trapped by G-Men | 1937 | Lefty | Movie |
| Great Guy | 1936 | Pete Reilly | Movie |
| Strike Me Pink | 1936 | Killer | Movie |
| Wedding Present | 1936 | Squinty | Movie |
| Kelly the Second | 1936 | Ike Arnold | Movie |
| Mister Cinderella | 1936 | Detective McNutt | Movie |
| Spendthrift | 1936 | Bill McGuire | Movie |
| The Case Against Mrs. Ames | 1936 | Sid | Movie |
| All American Chump | 1936 | Pudgy Murphy | Movie |
| Career Woman | 1936 | Doc Curley | Movie |
| Here Comes Trouble | 1936 | Crowley | Movie |
| Hideaway Girl | 1936 | Bugs Murphy | Movie |
| Woman Trap | 1936 | George Meade (as Ed Brophy) | Movie |
| China Seas | 1935 | Timmons | Movie |
| Devil Dogs of the Air | 1935 | Undetermined Role (scenes deleted) | Movie |
| I Live My Life | 1935 | Pete (uncredited) | Movie |
| Mad Love | 1935 | Rollo | Movie |
| Naughty Marietta | 1935 | Zeke | Movie |
| People Will Talk | 1935 | Pete Ranse | Movie |
| Remember Last Night? | 1935 | Maxie | Movie |
| The Whole Town's Talking | 1935 | 'Slugs' Martin | Movie |
| 1,000 Dollars a Minute | 1935 | Benny Dolan | Movie |
| Shadow of Doubt | 1935 | Fred Wilcox | Movie |
| Show Them No Mercy! | 1935 | Buzz | Movie |
| She Gets Her Man | 1935 | Flash (as Eddie Brophy) | Movie |
| Death on the Diamond | 1934 | Grogan | Movie |
| Evelyn Prentice | 1934 | Eddie Delaney | Movie |
| Forsaking All Others | 1934 | | Movie |
| Hide-Out | 1934 | Detective Britt | Movie |
| The Thin Man | 1934 | Morelli | Movie |
| Have a Heart | 1934 | Mac (uncredited) | Movie |
| Paris Interlude | 1934 | Ham | Movie |
| Sequoia | 1934 | Forest Ranger Pete (uncredited) | Movie |
| The Poor Rich | 1934 | Flannigan | Movie |
| I'll Fix It | 1934 | Tilly Tilson | Movie |
| Broadway to Hollywood | 1933 | Joe Mannion (uncredited) | Movie |
| Beer and Pretzels | 1933 | Theater Manager (uncredited) | Short Film |
| What-No Beer? | 1933 | Spike Moran | Movie |
| Hello Pop! | 1933 | Brophy (uncredited) | Short Film |
| Flesh | 1932 | Dolan - a Referee | Movie |
| Freaks | 1932 | Rollo Brother | Movie |
| Skyscraper Souls | 1932 | Man in Elevator (uncredited) | Movie |
| Speak Easily | 1932 | Reno | Movie |
| The Beast of the City | 1932 | Police Dispatcher (uncredited) | Movie |
| The Passionate Plumber | 1932 | Man Outside Beauty Parlor (uncredited) | Movie |
| Prosperity | 1932 | Ice Cream Salesman (uncredited) | Movie |
| A Free Soul | 1931 | Slouch (uncredited) | Movie |
| Parlor, Bedroom and Bath | 1931 | Detective | Movie |
| Sporting Blood | 1931 | Newsreel Cameraman (uncredited) | Movie |
| The Big Shot | 1931 | Undetermined Supporting Role (scenes deleted) | Movie |
| The Champ | 1931 | Tim | Movie |
| A Dangerous Affair | 1931 | Nelson | Movie |
| Doughboys | 1930 | Sergeant Brophy | Movie |
| Free and Easy | 1930 | Benny - The Stage Manager (uncredited) | Movie |
| Our Blushing Brides | 1930 | Joe Munsey | Movie |
| Paid | 1930 | Burglar (uncredited) | Movie |
| Estrellados | 1930 | Assistant Director (uncredited) | Movie |
| Remote Control | 1930 | Al | Movie |
| Those Three French Girls | 1930 | Yank | Movie |
| The Cameraman | 1928 | Man in Bath-House (uncredited) | Movie |
| Spring Fever | 1927 | Golf Game Spectator (uncredited) | Movie |
| West Point | 1927 | Team Manager (uncredited) | Movie |
| The Sign on the Door | 1921 | Newspaper Photographer (uncredited) | Movie |
| Yes or No | 1920 | Tom Martin (as Edward S. Brophy) | Movie |
